The Millennium Institute on Immunology and Immunotherapy, MIII, is a scientific initiative that brings together researchers from the Pontificia Universidad Católica de Chile, Universidad de Chile and Universidad Andrés Bello, which perform basic research in immunology with the envision to obtain practical applications in immunotherapy, as new immunological therapies, vaccines and pharmacological solutions. Research performed at MIII is aimed at fully understanding the functioning of the immune system to develop new therapies to cope with human diseases related to cancer, autoimmunity, infections, cardiovascular pathologies and endocrine disorders.